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Agonist-Directed Desensitization of the β(2)-Adrenergic Receptor

The β(2)-adrenergic receptor (β(2)AR) agonists with reduced tachyphylaxis may offer new therapeutic agents with improved tolerance profile. However, receptor desensitization assays are often inferred at the single signaling molecule level, thus ligand-directed desensitization is poorly understood. H...

詳細記述

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書誌詳細
主要な著者: Goral, Vasiliy, Jin, Yan, Sun, Haiyan, Ferrie, Ann M., Wu, Qi, Fang, Ye
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082563/
https://ncbi.nlm.nih.gov/pubmed/21541288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019282
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