Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells

Tumors express a wide variety of both mutated and nonmutated Ags. Whether these tumor Ags are broadly recognized as self or foreign by the immune system is currently unclear. Using an autochthonous prostate cancer model in which hemagglutinin (HA) is specifically expressed in the tumor (ProHA × TRAM...

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Библиографические подробности
Главные авторы: Getnet, Derese, Maris, Charles H., Hipkiss, Edward L., Grosso, Joseph F., Harris, Timothy J., Yen, Hung-Rong, Bruno, Tullia C., Wada, Satoshi, Adler, Adam, Georgantas, Robert W., Jie, Chunfa, Goldberg, Monica V., Pardoll, Drew M., Drake, Charles G.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082355/
https://ncbi.nlm.nih.gov/pubmed/19342643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803400
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