Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells

Tumors express a wide variety of both mutated and nonmutated Ags. Whether these tumor Ags are broadly recognized as self or foreign by the immune system is currently unclear. Using an autochthonous prostate cancer model in which hemagglutinin (HA) is specifically expressed in the tumor (ProHA × TRAM...

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Detalhes bibliográficos
Main Authors: Getnet, Derese, Maris, Charles H., Hipkiss, Edward L., Grosso, Joseph F., Harris, Timothy J., Yen, Hung-Rong, Bruno, Tullia C., Wada, Satoshi, Adler, Adam, Georgantas, Robert W., Jie, Chunfa, Goldberg, Monica V., Pardoll, Drew M., Drake, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082355/
https://ncbi.nlm.nih.gov/pubmed/19342643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803400
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