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Anti-Tumor Effects of Endogenous Prostate Cancer Specific CD8 T Cells in a Murine TCR Transgenic Model

BACKGROUND: The CD8 T cell response to prostate and other cancers is often functionally diminished or absent. This may occur via deletion of tumor-specific T cells, through acquisition of an anergic phenotype, or via active suppression mediated by another population of cells. METHODS: We used a doub...

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Detalhes bibliográficos
Main Authors: Bruno, Tullia C., Rothwell, Cristin, Grosso, Joseph F., Getnet, Derese, Yen, Hung Rong, Durham, Nicholas M., Netto, George, Pardoll, Drew M., Drake, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248615/
https://ncbi.nlm.nih.gov/pubmed/21761425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21453
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