The La antigen inhibits the activation of the interferon-inducible protein kinase PKR by sequestering and unwinding double-stranded RNA.

Παρόμοια τεκμήρια

• Involvement of the double-stranded-RNA-dependent kinase PKR in interferon expression and interferon-mediated antiviral activity.
  ανά: Der, S D, κ.ά.
  Έκδοση: (1995)
• West Nile Virus-Induced Interferon Production Is Mediated by the Double-Stranded RNA-Dependent Protein Kinase PKR
  ανά: Gilfoy, Felicia D., κ.ά.
  Έκδοση: (2007)
• The mouse antiphosphotyrosine immunoreactive kinase, TIK, is indistinguishable from the double-stranded RNA-dependent, interferon-induced protein kinase, PKR.
  ανά: Baier, L J, κ.ά.
  Έκδοση: (1993)
• Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways.
  ανά: Wong, A H, κ.ά.
  Έκδοση: (1997)
• The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins.
  ανά: Lee, T G, κ.ά.
  Έκδοση: (1994)