The La antigen inhibits the activation of the interferon-inducible protein kinase PKR by sequestering and unwinding double-stranded RNA.

The La (SS-B) autoimmune antigen is an RNA-binding protein that is present in both nucleus and cytoplasm of eukaryotic cells. The spectrum of RNAs that interact with the La antigen includes species which also bind to the interferon-inducible protein kinase PKR. We have investigated whether the La an...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

I whakaputaina i:	Nucleic Acids Res
Ngā kaituhi matua:	Xiao, Q, Sharp, T V, Jeffrey, I W, James, M C, Pruijn, G J, van Venrooij, W J, Clemens, M J
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Oxford University Press 1994
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7518914/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.13.2512
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!