Загрузка...

Structure, Energetics and Dynamics of Binding Coactivator Peptide to Human Retinoid X Receptor Alpha Ligand Binding Domain Complex with 9-cis-Retinoic Acid

Retinoid X receptors (RXRs) are ligand-dependent nuclear receptors, which are activated by the potent agonist 9-cis retinoic acid (9cRA). 9cRA binds to the ligand binding domain (LBD) of RXRs, and recruits coactivator proteins for gene transcription. Using isothermal titration calorimetry, the bindi...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Xia, Gang, Boerma, LeeAnn J, Cox, Bryan D, Qiu, Cheng, Kang, Sebyung, Smith, Craig D, Renfrow, Matthew B, Muccio, Donald D
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081989/
https://ncbi.nlm.nih.gov/pubmed/21049972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101288y
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!