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TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin

That TLR-based vaccine adjuvants maintain function in TLR-deficient hosts highlights that their mechanism of function remains incompletely understood. Thus, we examined the ability of flagellin to induce cytokines and elicit/promote murine antibody responses upon deletion of the flagellin receptors...

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Detalhes bibliográficos
Main Authors: Vijay-Kumar, Matam, Carvalho, Frederic A., Aitken, Jesse D., Fifadara, Nimita H., Gewirtz, Andrew T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081661/
https://ncbi.nlm.nih.gov/pubmed/21072873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040421
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