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TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin
That TLR-based vaccine adjuvants maintain function in TLR-deficient hosts highlights that their mechanism of function remains incompletely understood. Thus, we examined the ability of flagellin to induce cytokines and elicit/promote murine antibody responses upon deletion of the flagellin receptors...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081661/ https://ncbi.nlm.nih.gov/pubmed/21072873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040421 |
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