Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin

Bacterial flagellin is a unique pathogen-associated molecular pattern (PAMP), which can be recognized by surface localized Toll-like receptor 5 (TLR5) and the cytosolic NOD-like receptor (NLR) protein 4 (NLRC4) receptors. Activation of the TLR5 and/or NLRC4 signaling pathways by flagellin and the re...

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Publicat a:Cell Mol Immunol
Autors principals: Li, Wei, Yang, Jingyi, Zhang, Ejuan, Zhong, Maohua, Xiao, Yang, Yu, Jie, Zhou, Dihan, Cao, Yuan, Yang, Yi, Li, Yaoming, Yan, Huimin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947818/
https://ncbi.nlm.nih.gov/pubmed/25914934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.33
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