Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution

A high-resolution structure of a ligand-bound, soluble form of human monoglyceride lipase (MGL) is presented. The structure highlights a novel conformation of the regulatory lid-domain present in the lipase family as well as the binding mode of a pharmaceutically relevant reversible inhibitor. Analy...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Schalk-Hihi, Céline, Schubert, Carsten, Alexander, Richard, Bayoumy, Shariff, Clemente, Jose C, Deckman, Ingrid, DesJarlais, Renee L, Dzordzorme, Keli C, Flores, Christopher M, Grasberger, Bruce, Kranz, James K, Lewandowski, Frank, Liu, Li, Ma, Hongchang, Maguire, Diane, Macielag, Mark J, McDonnell, Mark E, Mezzasalma Haarlander, Tara, Miller, Robyn, Milligan, Cindy, Reynolds, Charles, Kuo, Lawrence C
格式: Artigo
語言:Inglês
出版: Wiley Subscription Services, Inc., A Wiley Company 2011
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081545/
https://ncbi.nlm.nih.gov/pubmed/21308848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.596
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍