A novel fluorogenic substrate for the measurement of endothelial lipase activity

Endothelial lipase (EL) is a phospholipase A(1) (PLA(1)) enzyme that hydrolyzes phospholipids at the sn-1 position to produce lysophospholipids and free fatty acids. Measurement of the PLA(1) activity of EL is usually accomplished by the use of substrates that are also hydrolyzed by lipases in other...

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Bibliographische Detailangaben
Hauptverfasser: Darrow, Andrew L., Olson, Matthew W., Xin, Hong, Burke, Sharon L., Smith, Charles, Schalk-Hihi, Celine, Williams, Robyn, Bayoumy, Shariff S., Deckman, Ingrid C., Todd, Matthew J., Damiano, Bruce P., Connelly, Margery A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023558/
https://ncbi.nlm.nih.gov/pubmed/21062953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D007971
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