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A novel fluorogenic substrate for the measurement of endothelial lipase activity

Endothelial lipase (EL) is a phospholipase A(1) (PLA(1)) enzyme that hydrolyzes phospholipids at the sn-1 position to produce lysophospholipids and free fatty acids. Measurement of the PLA(1) activity of EL is usually accomplished by the use of substrates that are also hydrolyzed by lipases in other...

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Bibliographic Details
Main Authors: Darrow, Andrew L., Olson, Matthew W., Xin, Hong, Burke, Sharon L., Smith, Charles, Schalk-Hihi, Celine, Williams, Robyn, Bayoumy, Shariff S., Deckman, Ingrid C., Todd, Matthew J., Damiano, Bruce P., Connelly, Margery A.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023558/
https://ncbi.nlm.nih.gov/pubmed/21062953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D007971
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