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Sensitive Dual Color In Vivo Bioluminescence Imaging Using a New Red Codon Optimized Firefly Luciferase and a Green Click Beetle Luciferase

BACKGROUND: Despite a plethora of bioluminescent reporter genes being cloned and used for cell assays and molecular imaging purposes, the simultaneous monitoring of multiple events in small animals is still challenging. This is partly attributable to the lack of optimization of cell reporter gene ex...

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Autors principals: Mezzanotte, Laura, Que, Ivo, Kaijzel, Eric, Branchini, Bruce, Roda, Aldo, Löwik, Clemens
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081340/
https://ncbi.nlm.nih.gov/pubmed/21544210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019277
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