Sensitive Dual Color In Vivo Bioluminescence Imaging Using a New Red Codon Optimized Firefly Luciferase and a Green Click Beetle Luciferase

BACKGROUND: Despite a plethora of bioluminescent reporter genes being cloned and used for cell assays and molecular imaging purposes, the simultaneous monitoring of multiple events in small animals is still challenging. This is partly attributable to the lack of optimization of cell reporter gene ex...

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Main Authors: Mezzanotte, Laura, Que, Ivo, Kaijzel, Eric, Branchini, Bruce, Roda, Aldo, Löwik, Clemens
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081340/
https://ncbi.nlm.nih.gov/pubmed/21544210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019277
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