Sensitive Dual Color In Vivo Bioluminescence Imaging Using a New Red Codon Optimized Firefly Luciferase and a Green Click Beetle Luciferase

BACKGROUND: Despite a plethora of bioluminescent reporter genes being cloned and used for cell assays and molecular imaging purposes, the simultaneous monitoring of multiple events in small animals is still challenging. This is partly attributable to the lack of optimization of cell reporter gene ex...

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Main Authors: Mezzanotte, Laura, Que, Ivo, Kaijzel, Eric, Branchini, Bruce, Roda, Aldo, Löwik, Clemens
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081340/
https://ncbi.nlm.nih.gov/pubmed/21544210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019277
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