Prostaglandin E(2)–prostoglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression

UV radiation induces systemic immunosuppression. Because nonsteroidal anti-inflammatory drugs suppress UV-induced immunosuppression, prostanoids have been suspected as a crucial mediator of this UV effect. However, the identity of the prostanoid involved and its mechanism of action remain unclear. H...

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Autors principals: Soontrapa, Kitipong, Honda, Tetsuya, Sakata, Daiji, Yao, Chengcan, Hirata, Takako, Hori, Shohei, Matsuoka, Toshiyuki, Kita, Yoshihiro, Shimizu, Takao, Kabashima, Kenji, Narumiya, Shuh
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081002/
https://ncbi.nlm.nih.gov/pubmed/21460251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018625108
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