Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells

Immunocytochemical studies have shown that protocadherin-15 (PCDH15) and cadherin-23 (CDH23) are associated with tip links, structures thought to gate the mechanotransducer channels of hair cells in the sensory epithelia of the inner ear. The present report describes functional and structural analys...

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Hlavní autoři: Alagramam, Kumar N., Goodyear, Richard J., Geng, Ruishuang, Furness, David N., van Aken, Alexander F. J., Marcotti, Walter, Kros, Corné J., Richardson, Guy P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080917/
https://ncbi.nlm.nih.gov/pubmed/21532990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019183
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