Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells

Immunocytochemical studies have shown that protocadherin-15 (PCDH15) and cadherin-23 (CDH23) are associated with tip links, structures thought to gate the mechanotransducer channels of hair cells in the sensory epithelia of the inner ear. The present report describes functional and structural analys...

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Detaylı Bibliyografya
Asıl Yazarlar: Alagramam, Kumar N., Goodyear, Richard J., Geng, Ruishuang, Furness, David N., van Aken, Alexander F. J., Marcotti, Walter, Kros, Corné J., Richardson, Guy P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080917/
https://ncbi.nlm.nih.gov/pubmed/21532990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019183
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