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Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175
The cyclin-dependent kinase CDK9/cyclin T1 induces HIV-1 transcription by phosphorylating the carboxyterminal domain (CTD) of RNA polymerase II (RNAPII). CDK9 activity is regulated by protein phosphatase-1 (PP1) which was previously shown to dephosphorylate CDK9 Thr186. Here, we analyzed the effect...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080879/ https://ncbi.nlm.nih.gov/pubmed/21533037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018985 |
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