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Linking Microscopic Spatial Patterns of Tissue Destruction in Emphysema to Macroscopic Decline in Stiffness Using a 3D Computational Model

Pulmonary emphysema is a connective tissue disease characterized by the progressive destruction of alveolar walls leading to airspace enlargement and decreased elastic recoil of the lung. However, the relationship between microscopic tissue structure and decline in stiffness of the lung is not well...

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Библиографические подробности
Главные авторы: Parameswaran, Harikrishnan, Majumdar, Arnab, Suki, Béla
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080851/
https://ncbi.nlm.nih.gov/pubmed/21533072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001125
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