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Proteoglycans Maintain Lung Stability in an Elastase-Treated Mouse Model of Emphysema

Extracellular matrix remodeling and tissue rupture contribute to the progression of emphysema. Lung tissue elasticity is governed by the tensile stiffness of fibers and the compressive stiffness of proteoglycans. It is not known how proteoglycan remodeling affects tissue stability and destruction in...

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Detalhes bibliográficos
Main Authors: Takahashi, Ayuko, Majumdar, Arnab, Parameswaran, Harikrishnan, Bartolák-Suki, Erzsébet, Suki, Béla
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091854/
https://ncbi.nlm.nih.gov/pubmed/24450478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0179OC
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