Mechanical Forces Regulate Elastase Activity and Binding Site Availability in Lung Elastin

Many fundamental cellular and extracellular processes in the body are mediated by enzymes. At the single molecule level, enzyme activity is influenced by mechanical forces. However, the effects of mechanical forces on the kinetics of enzymatic reactions in complex tissues with intact extracellular m...

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Main Authors: Jesudason, Rajiv, Sato, Susumu, Parameswaran, Harikrishnan, Araujo, Ascanio D., Majumdar, Arnab, Allen, Philip G., Bartolák-Suki, Erzsébet, Suki, Béla
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2010
Ábhair:
Protein
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965944/
https://ncbi.nlm.nih.gov/pubmed/21044606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.018
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