Mechanical Forces Regulate Elastase Activity and Binding Site Availability in Lung Elastin

Many fundamental cellular and extracellular processes in the body are mediated by enzymes. At the single molecule level, enzyme activity is influenced by mechanical forces. However, the effects of mechanical forces on the kinetics of enzymatic reactions in complex tissues with intact extracellular m...

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Autori principali: Jesudason, Rajiv, Sato, Susumu, Parameswaran, Harikrishnan, Araujo, Ascanio D., Majumdar, Arnab, Allen, Philip G., Bartolák-Suki, Erzsébet, Suki, Béla
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2010
Soggetti:
Protein
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965944/
https://ncbi.nlm.nih.gov/pubmed/21044606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.018
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