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Proteoglycans Maintain Lung Stability in an Elastase-Treated Mouse Model of Emphysema

Extracellular matrix remodeling and tissue rupture contribute to the progression of emphysema. Lung tissue elasticity is governed by the tensile stiffness of fibers and the compressive stiffness of proteoglycans. It is not known how proteoglycan remodeling affects tissue stability and destruction in...

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Autors principals: Takahashi, Ayuko, Majumdar, Arnab, Parameswaran, Harikrishnan, Bartolák-Suki, Erzsébet, Suki, Béla
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091854/
https://ncbi.nlm.nih.gov/pubmed/24450478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0179OC
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