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A computational model of the response of adherent cells to stretch and changes in substrate stiffness

Cells in the body exist in a dynamic mechanical environment where they are subject to mechanical stretch as well as changes in composition and stiffness of the underlying extracellular matrix (ECM). However, the underlying mechanisms by which cells sense and adapt to their dynamic mechanical environ...

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Detalhes bibliográficos
Main Authors: Parameswaran, Harikrishnan, Lutchen, Kenneth R., Suki, Béla
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972747/
https://ncbi.nlm.nih.gov/pubmed/24408996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00962.2013
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