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Linking Microscopic Spatial Patterns of Tissue Destruction in Emphysema to Macroscopic Decline in Stiffness Using a 3D Computational Model

Pulmonary emphysema is a connective tissue disease characterized by the progressive destruction of alveolar walls leading to airspace enlargement and decreased elastic recoil of the lung. However, the relationship between microscopic tissue structure and decline in stiffness of the lung is not well...

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Detalhes bibliográficos
Main Authors: Parameswaran, Harikrishnan, Majumdar, Arnab, Suki, Béla
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080851/
https://ncbi.nlm.nih.gov/pubmed/21533072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001125
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