Macrophage IL-12p70 Signaling Prevents HSV-1–Induced CNS Autoimmunity Triggered by Autoaggressive CD4(+) Tregs

PURPOSE. CD4(+)CD25(+)FoxP3(+) naturally occurring regulatory T cells (Tregs) maintain self-tolerance and function to suppress overly exuberant immune responses. However, it is unclear whether innate immune cells modulate Treg function. Here the authors examined the role of innate immunity in lympho...

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Xehetasun bibliografikoak
Egile Nagusiak: Mott, Kevin R., Gate, David, Zandian, Mandana, Allen, Sariah J., Rajasagi, Naveen Kumar, van Rooijen, Nico, Chen, Shuang, Arditi, Moshe, Rouse, Barry T., Flavell, Richard A., Town, Terrence, Ghiasi, Homayon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Association for Research in Vision and Ophthalmology, Inc. 2011
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080735/
https://ncbi.nlm.nih.gov/pubmed/21220560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6536
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