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TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling

TAR DNA-binding protein 43 (TDP-43) plays a key role in the neurodegenerative diseases including amyotrophic lateral sclerosis and frontotemporal lobar degeneration. The nature of the TDP-43-mediated neurotoxicity associated with these diseases is not yet understood. Here, we have established transg...

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Sonraí Bibleagrafaíochta
Main Authors: Zhang, Tao, Mullane, Patrick C., Periz, Goran, Wang, Jiou
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080607/
https://ncbi.nlm.nih.gov/pubmed/21355045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr076
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