Pentaerithrityl tetranitrate improves angiotensin II induced vascular dysfunction via induction of heme oxygenase-1

The organic nitrate pentaerithrityl tetranitrate treatment is devoid of nitrate tolerance, which has been attributed to the induction of the antioxidant enzyme heme oxygenase-1. With the present study we tested, whether chronic treatment with pentaerithrityl tetranitrate can improve angiotensin-II i...

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Autors principals: Schuhmacher, Swenja, Wenzel, Philip, Schulz, Eberhard, Oelze, Matthias, Mang, Christian, Kamuf, Jens, Gori, Tommaso, Jansen, Thomas, Knorr, Maike, Karbach, Susanne, Hortmann, Marcus, Mäthner, Falk, Bhatnagar, Aruni, Förstermann, Ulrich, Li, Huige, Münzel, Thomas, Daiber, Andreas
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080599/
https://ncbi.nlm.nih.gov/pubmed/20157049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.149542
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