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α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation

OBJECTIVE: Besides its well described metabolic effects, vascular AMP-activated protein kinase (AMPK) can activate endothelial NO synthase, promotes angiogenesis and limits endothelial cell apoptosis. The current study was designed to study the effects of α1AMPK deletion during vascular disease in v...

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Detalhes bibliográficos
Main Authors: Schuhmacher, Swenja, Foretz, Marc, Knorr, Maike, Jansen, Thomas, Hortmann, Marcus, Wenzel, Philip, Oelze, Matthias, Kleschyov, Andrei L., Daiber, Andreas, Keaney, John F., Wegener, Gerhard, Lackner, Karl, Münzel, Thomas, Viollet, Benoit, Schulz, Eberhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066307/
https://ncbi.nlm.nih.gov/pubmed/21205985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.219543
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