α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation

OBJECTIVE: Besides its well described metabolic effects, vascular AMP-activated protein kinase (AMPK) can activate endothelial NO synthase, promotes angiogenesis and limits endothelial cell apoptosis. The current study was designed to study the effects of α1AMPK deletion during vascular disease in v...

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Main Authors: Schuhmacher, Swenja, Foretz, Marc, Knorr, Maike, Jansen, Thomas, Hortmann, Marcus, Wenzel, Philip, Oelze, Matthias, Kleschyov, Andrei L., Daiber, Andreas, Keaney, John F., Wegener, Gerhard, Lackner, Karl, Münzel, Thomas, Viollet, Benoit, Schulz, Eberhard
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066307/
https://ncbi.nlm.nih.gov/pubmed/21205985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.219543
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