SHPRH and HLTF Act in a Damage-specific Manner to Coordinate Different Forms of Post-replication Repair and Prevent Mutagenesis

Post-replication repair (PRR) pathways play important roles in restarting stalled replication forks and regulating mutagenesis. In yeast, Rad5-mediated damage avoidance and Rad18-mediated translesion synthesis (TLS) are two forms of PRR. Two Rad5-related proteins, SHPRH and HLTF, have been identifie...

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Bibliographic Details
Main Authors: Lin, Jia-Ren, Zeman, Michelle K., Chen, Jia-Yun, Yee, Muh-Ching, Cimprich, Karlene A.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080461/
https://ncbi.nlm.nih.gov/pubmed/21396873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.02.026
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