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SHPRH and HLTF Act in a Damage-specific Manner to Coordinate Different Forms of Post-replication Repair and Prevent Mutagenesis
Post-replication repair (PRR) pathways play important roles in restarting stalled replication forks and regulating mutagenesis. In yeast, Rad5-mediated damage avoidance and Rad18-mediated translesion synthesis (TLS) are two forms of PRR. Two Rad5-related proteins, SHPRH and HLTF, have been identifie...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3080461/ https://ncbi.nlm.nih.gov/pubmed/21396873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.02.026 |
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