Poly(ADP-Ribose) Polymerases PARP1 and PARP2 Modulate Topoisomerase II Beta (TOP2B) Function During Chromatin Condensation in Mouse Spermiogenesis

To achieve the specialized nuclear structure in sperm necessary for fertilization, dramatic chromatin reorganization steps in developing spermatids are required where histones are largely replaced first by transition proteins and then by protamines. This entails the transient formation of DNA strand...

Full description

Saved in:
Bibliographic Details
Main Authors: Meyer-Ficca, Mirella L., Lonchar, Julia D., Ihara, Motomasa, Meistrich, Marvin L., Austin, Caroline A., Meyer, Ralph G.
Format: Artigo
Language:Inglês
Published: Society for the Study of Reproduction, Inc. 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080419/
https://ncbi.nlm.nih.gov/pubmed/21228215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.110.090035
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items