In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles

Gemcitabine (Gemzar®) is the first line treatment for pancreatic cancer and often used in combination therapy for non-small cell lung, ovarian, and metastatic breast cancers. Although extremely toxic to a variety of tumor cells in culture, the clinical outcome of gemcitabine treatment still needs im...

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Main Authors: Sloat, Brian R., Sandoval, Michael A., Li, Dong, Chung, Woon-Gye, Lansakara-P., Dharmika S. P., Proteau, Philip J., Kiguchi, Kaoru, DiGiovanni, John, Cui, Zhengrong
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079786/
https://ncbi.nlm.nih.gov/pubmed/21371545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.02.037
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