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Repetitive Nerve Stimulation Transiently Opens the Mitochondrial Permeability Transition Pore in Motor Nerve Terminals of Symptomatic Mutant SOD1 Mice

Mitochondria in motor nerve terminals temporarily sequester large Ca(2+) loads during repetitive stimulation. In wild-type mice this Ca(2+) uptake produces a small (<5 mV), transient depolarization of the mitochondrial membrane potential (Ψ(m), motor nerve stimulated with at 100 Hz for 5 s). We d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Nguyen, Khanh T., Barrett, John N., García-Chacón, Luis, David, Gavriel, Barrett, Ellen F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079773/
https://ncbi.nlm.nih.gov/pubmed/21310237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.01.031
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