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Mitochondrial Ca(2+) uptake prevents desynchronization of quantal release and minimizes depletion during repetitive stimulation of mouse motor nerve terminals

We investigated how inhibition of mitochondrial Ca(2+) uptake affects transmitter release from mouse motor terminals during brief trains of action potentials (500 at 50 Hz) in physiological bath [Ca(2+)]. When mitochondrial Ca(2+) uptake was inhibited by depolarizing mitochondria with antimycin A1 o...

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Détails bibliographiques
Auteurs principaux: David, Gavriel, Barrett, Ellen F
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342850/
https://ncbi.nlm.nih.gov/pubmed/12588898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.035196
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