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Absence of Ataxin-3 Leads to Enhanced Stress Response in C. elegans
Ataxin-3, the protein involved in Machado-Joseph disease, is able to bind ubiquitylated substrates and act as a deubiquitylating enzyme in vitro, and it has been involved in the modulation of protein degradation by the ubiquitin-proteasome pathway. C. elegans and mouse ataxin-3 knockout models are v...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079722/ https://ncbi.nlm.nih.gov/pubmed/21526185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018512 |
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