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Nucleocytoplasmic Shuttling Activity of Ataxin-3
Spinocerebellar ataxia type-3, also known as Machado-Joseph Disease (MJD), is one of many inherited neurodegenerative disorders caused by polyglutamine-encoding CAG repeat expansions in otherwise unrelated genes. Disease protein misfolding and aggregation, often within the nucleus of affected neuron...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688764/ https://ncbi.nlm.nih.gov/pubmed/19503814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005834 |
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