Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models

Different neurodegenerative diseases are caused by aberrant elongation of repeated glutamine sequences normally found in particular human proteins. Although the proteins involved are ubiquitously distributed in human tissues, toxicity targets only defined neuronal populations. Changes caused by an e...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Matos, Carlos A., Nóbrega, Clévio, Louros, Susana R., Almeida, Bruno, Ferreiro, Elisabete, Valero, Jorge, Pereira de Almeida, Luís, Macedo-Ribeiro, Sandra, Carvalho, Ana Luísa
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754714/
https://ncbi.nlm.nih.gov/pubmed/26880203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506025
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