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Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models

Different neurodegenerative diseases are caused by aberrant elongation of repeated glutamine sequences normally found in particular human proteins. Although the proteins involved are ubiquitously distributed in human tissues, toxicity targets only defined neuronal populations. Changes caused by an e...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Matos, Carlos A., Nóbrega, Clévio, Louros, Susana R., Almeida, Bruno, Ferreiro, Elisabete, Valero, Jorge, Pereira de Almeida, Luís, Macedo-Ribeiro, Sandra, Carvalho, Ana Luísa
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754714/
https://ncbi.nlm.nih.gov/pubmed/26880203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506025
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