Non-Esterified Fatty Acids Generate Distinct Low-Molecular Weight Amyloid-β (Aβ42) Oligomers along Pathway Different from Fibril Formation

Amyloid-β (Aβ) peptide aggregation is known to play a central role in the etiology of Alzheimer’s disease (AD). Among various aggregates, low-molecular weight soluble oligomers of Aβ are increasingly believed to be the primary neurotoxic agents responsible for memory impairment. Anionic interfaces a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kumar, Amit, Bullard, Rebekah L., Patel, Pritesh, Paslay, Lea C., Singh, Dipti, Bienkiewicz, Ewa A., Morgan, Sarah E., Rangachari, Vijayaraghavan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079704/
https://ncbi.nlm.nih.gov/pubmed/21526230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018759
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi