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The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End Joining Pathway

Double-strand DNA breaks are common events in eukaryotic cells, and there are two major pathways for repairing them: homologous recombination and nonhomologous DNA end joining (NHEJ). The diverse causes of DSBs result in a diverse chemistry of DNA ends that must be repaired. Across NHEJ evolution, t...

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Bibliografske podrobnosti
Glavni avtor: Lieber, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079308/
https://ncbi.nlm.nih.gov/pubmed/20192759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biochem.052308.093131
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