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The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End Joining Pathway
Double-strand DNA breaks are common events in eukaryotic cells, and there are two major pathways for repairing them: homologous recombination and nonhomologous DNA end joining (NHEJ). The diverse causes of DSBs result in a diverse chemistry of DNA ends that must be repaired. Across NHEJ evolution, t...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079308/ https://ncbi.nlm.nih.gov/pubmed/20192759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.biochem.052308.093131 |
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