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Proinflammatory role of aquaporin-4 in autoimmune neuroinflammation

Aquaporin-4 (AQP4) deficiency in mice reduces neuroinflammation in experimental autoimmune encephalomyelitis (EAE) produced by active immunization with myelin oligodendrocyte glycoprotein peptide (MOG). Potential mechanisms for the protective effect of AQP4 deficiency were investigated, including AQ...

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Detalhes bibliográficos
Main Authors: Li, Lihua, Zhang, Hua, Varrin-Doyer, Michel, Zamvil, Scott S., Verkman, A. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079299/
https://ncbi.nlm.nih.gov/pubmed/21257712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-177279
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