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Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice

BACKGROUND: The involvement of astrocyte water channel aquaporin-4 (AQP4) in autoimmune diseases of the central nervous system has been suggested following the identification of AQP4 autoantibodies in neuromyelitis optica, an inflammatory demyelinating disease. RESULTS: We investigated the involveme...

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Detalhes bibliográficos
Main Authors: Li, Lihua, Zhang, Hua, Verkman, AS
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152780/
https://ncbi.nlm.nih.gov/pubmed/19660138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-94
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