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Greatly improved survival and neuroprotection in aquaporin-4-knockout mice following global cerebral ischemia
Aquaporin-4 (AQP4), the principal water channel in astrocytes, is involved in brain water movement, inflammation, and neuroexcitation. In this study, there was strong neuroprotection in mice lacking AQP4 in a model of global cerebral ischemia produced by transient, bilateral carotid artery occlusion...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898642/ https://ncbi.nlm.nih.gov/pubmed/24186965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-231274 |
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