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DNA looping by the HMG-box domains of HMG1 and modulation of DNA binding by the acidic C-terminal domain.

We have compared HMG1 with the product of tryptic removal of its acidic C-terminal domain termed HMG3, which contains two 'HMG-box' DNA-binding domains. (i) HMG3 has a higher affinity for DNA than HMG1. (ii) Both HMG1 and HMG3 supercoil circular DNA in the presence of topoisomerase I. Supe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stros, M, Stokrová, J, Thomas, J O
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1994
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC307928/
https://ncbi.nlm.nih.gov/pubmed/8152909
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