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Solution structure of a DNA-binding domain from HMG1.

We have determined the tertiary structure of box 2 from hamster HMG1 using bacterial expression and 3D NMR. The all alpha-helical fold is in the form of a V-shaped arrowhead with helices along two edges and one rather flat face. This architecture is not related to any of the known DNA binding motifs...

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Bibliografiske detaljer
Main Authors: Read, C M, Cary, P D, Crane-Robinson, C, Driscoll, P C, Norman, D G
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331441/
https://ncbi.nlm.nih.gov/pubmed/8346022
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