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Characterization of the DNA binding and bending HMG domain of the yeast hypoxic repressor Rox1.

The yeast Rox1 hypoxic transcriptional repressor protein binds to and bends a specific DNA sequence through an HMG domain located at the N-terminus. To better understand the structure of Rox1 and how it interacts with DNA, 38 missense mutations in the HMG domain were isolated through a combination o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deckert, J, Khalaf, R A, Hwang, S M, Zitomer, R S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC148596/
https://ncbi.nlm.nih.gov/pubmed/10446242
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