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Combined Blockade of Src Kinase and Epidermal Growth Factor Receptor with Gemcitabine Overcomes STAT3-Mediated Resistance of Inhibition of Pancreatic Tumor Growth
PURPOSE: We previously established a mechanistic rationale for Src inhibition as a novel therapeutic target in pancreatic cancer and have shown that activated STAT3 is a biomarker of resistance to Src inhibition. The purpose of this study was to translate the current understanding of complementary a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079196/ https://ncbi.nlm.nih.gov/pubmed/21266529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1670 |
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